SPOILERS!!! (As if I have to say this in the beta test forum...)
After all that discussion, I was all primed and eager to at least get a few swings in on the Werewolf in Griffith Park. I even turned the damage floaters back on, so I could see how much damage I did.
And the answer is... none. Nada. Zilch. STR 4, Melee 5, and the Trama'Lama blade from Akeem (couldn't find it anywhere in the Hallowbrook) -- and the little damage floaters kept drifting up from his Kryptonian hide... 0... 0... 0...
Tried the SPAS15. Zero damage.
I tried 'Taste of Death' (Quietus 3), and this actually worked (somewhat), doing from 10 to 15 points of damage each strike -- Not sure why the damage varied. This made absolutely no impression on the Werewolf's health bar at the top of my screen. But even though this should have lowered his defenses somewhat, I was still doing no damage in Melee combat. Also, after spitting at him three times, for a total of 38 points of damage, the health bar was still totally full. Perhaps he regenerated too fast, I don't know.
So I finished him off the usual way, and proceeded to Santa Monica, where I saved my game and went back. Just before talking to Nines in Griffith Park, I maxed out everything, in an attempt to see just what would work.
Even with Strength, Melee and Blood Buff all at level 5, the Tal'mahe'ra blade still did zero (0) damage. My level 4 Quietus power, 'Baal's Caress' (poison blood on melee weapon) did not change this. Level 5 Quietus, 'Leech', did a whopping 1 point of damage. 'Taste of Death' still allegedly did damage, but his health bar didn't show any change. Either his health is unbelievably high, or he regenerates as quick as we used to do, before Blood Heal. Or both.
(As a side note, even after I killed him with the Observatory Telescope doors, the Damage bar was still up there... and full.)
Oh, BTW... the flamethrower did absolutely nothing to him. Except maybe kill a few of his fleas. There weren't even any zeros floating up. It's as if the flames didn't even exist for him. Good trick, that; wish he'd teach it to me.
Ultimate test... I put on God mode, and used Taste of Death and Leech for perhaps ten minutes, to see if I could make an impression in his health bar. Nothing. Either the damage floaters lie, or he regenerates too fast. Or maybe the health bar is what's broken.
I'll be honest; I was disappointed. I believe you really meant to give us a chance to kill him. But I think that whatever you did to make the werewolf 'killable' did not work. Not with Assamite Disciplines, anyway.